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In fact, AngII, via its AT 1 receptor, promotes cell growth, inflammation, vasoconstriction, apoptosis, production of extracellular matrix components and the release of ROS (198)

It is made by the body and does not need to be eaten in the diet

In melanoma, the response to ICIs can be enhanced by using Smac mimetics which have a direct impact on immune cells such as B cells, MDSCs, DCs, and cytotoxic T cells (Michie et al., 2020)