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**BPC-157, a synthetic gastric pentadecapeptide studied primarily in animal models for tissue repair, gut healing, and anti-inflammatory effects, remains unapproved by the FDA as a finished drug with only limited small-scale human data available.** It was placed in Category 2 in 2023 due to concerns over immunogenicity, peptide impurities, and insufficient safety information for compounding under Section 503A

In a head-to-head trial, 70% improved on copper peptides versus 40% on retinoids and 50% on vitamin C

This includes severe headaches, vision changes, shortness of breath, chest pain, rapid swelling, and fainting

A more honest reading shows promising signals in some areas and significant gaps in knee-specific outcomes