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Chronic use of these substances is strongly associated with persistent cognitive deficits, psychiatric symptoms, and, in some cases, neurovascular damage

Carotid Plaque Score for Stroke and Cardiovascular Risk Prediction in a Middle-Aged Cohort From the General Population

In mammalian cells, -glutamylcysteine synthetase is effectively inhibited by a GSH feedback, whereas glutathione synthetase is not subject to the negative feedback 9,30