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33,34 JNK translocates to mitochondria, binds to SH3 homologyassociated Brutons tyrosine kinase (BTK) binding protein (Sab) on the mitochondrial membrane, and subsequently inactivates a proto-oncogene tyrosine-protein kinase (Src) in mitochondria, eventually leading to the dysfunction of the ETC and the increased release of reactive oxygen species (ROS)

Approximately 17% of first opioid overdoses observed over the entire study period (5 to 11 years, depending on the study site) were fatal

doi: 10.1016/j.biopha.2022.113139

Abstract Autistic individuals with disproportionate megalencephaly (ASD-DM), characterized by enlarged brains relative to body height, have higher rates of intellectual disability and face more severe cognitive challenges than autistic children with average brain sizes

doi: 10.1016/j.biocel.2020.105876 164 MokEHKLeeTKW