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Interestingly, the gut microbiota plays a crucial role in regulating the spatiotemporal dynamic balance of the mucosal immune system and exhibits distinct immune regulatory characteristics in bacterial, viral, and fungal pneumonia

NPJ Parkinsons Dis 8(1):32 Jo EK, Kim JK, Shin DM, Sasakawa C (2016) Molecular mechanisms regulating NLRP3 inflammasome activation

this protein induces a peculiar form of cell death, now called ferroptosis, via an increase in ROS levels that subsequently inhibit the cystine uptake typically mediated by the repression of a key component of the cystine/glutamate antiporter 126