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[12] Antioxidant enzymes counterbalance redox signalling by eliminating the involved molecules, importantly superoxide anion and nitric oxide

In fact, these downstream effects of ROS production may ultimately be responsible for much of the bactericidal activities of ROS rather than direct damage by ROS themselves (Miralda et al., 2017)

Di Minno MND, Pezzullo S, Palmieri V, Coppola A, DAngelo A, Sampietro F, Cavalca V, Tremoli E, Di Minno G (2011) Genotype-independent in vivo oxidative stress following a methionine loading test: maximal platelet activation in subjects with early-onset thrombosis

By using nanocarriers to transport drugs, drugs can be released when stimulated by the acidic tumor microenvironment, achieving stimulatory targeted delivery and verifying its targeting in vivo and in vitro

References de Oliveira, S., Rosowski, E