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BSO is an inhibitor of gamma glutamylcysteine synthetase (gamma GCs), Download Scientific Diagram Development of a mouse model expressing a bifunctional glutathione synthesizing enzyme to study glutathione limitation in vivo Journal of Biological Chemistry The glutathione cycle shapes synaptic glutamate activity PNAS The glutathione synthesis inhibitor buthionine sulfoximine synergistically enhanced melphalan activity against preclinical models of multiple myeloma Blood Cancer Journal Combination studies of platinum( ii ) based metallointercalators with buthionine S , R sulfoximine, 3 bromopyruvate, cisplatin or carboplatin Metallomics (RSC Publishing) DOI:10.1039 C3MT00191A
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