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"Glucagon-like peptide 1 (GLP-1)." Molecular Metabolism , 30, 72-130

Safety data lacks large-scale human trials, which limits verified dosage standards and long-term risk evaluation

68-week bone density data showed no significant changes from baseline

Liver-related discomfort stems from organ swelling that stretches the surrounding capsule, creating a characteristic dull ache in the upper right abdomen that may radiate to the shoulder

Appetite suppression was observed at doses 0.3 mg while significant reductions in circulating triglycerides, branched-chained amino-acids and fasting and postprandial glucagon levels were also seen, along with increasing insulin secretion