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In contrast, the hyphal form, mediated by the cAMP-dependent protein kinase-A (PKA) pathway, the mitogen-activated protein kinase [MAPK] cascade [75], and the calcium calmodulin-mediated signal transduction pathway, possesses the ability to invade the protective layers either by active penetration or by induced endocytosis [76]

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I think its like anxiety is over here and Parkinsons is over here, and akathisia is kind of in here somewhere, but its just another manifestation of not controlling where that energy is going