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These side effects are generally rare, but the injection should always be used under medical supervision

Inhibition strategy and regulation mechanism of sodium urate crystallization based on hydrogel

Potential clinical relevance While current PH therapies (i.e., prostacyclins, phosphodiesterase inhibitors, calcium channel blockers, endothelin receptor antagonists, or soluble guanylate cyclase stimulators) focus primarily on alleviating vasoconstriction as a symptomatic approach (215), the long-term therapeutic goal is to shift towards targeting mechanisms of disease onset and progression, including vascular remodeling and inflammation (215)

Emerging regulatory mechanisms and functions of biomolecular condensates: implications for therapeutic targets

PMID: 36084636