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Acute and long-term LC supplementation is beneficial in several pathologic conditions, including infectious diseases (including HIV), hemodialysis, cancer cachexia, and dystonia

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67 Pancreatitis may increase glycaemic variability (fluctuations in BG concentration over the day) and reduce the chance of remission, 66,68 but other factors are also involved and a diagnosis of pancreatitis does not preclude good control of DM or remission

Choline may increase cholinergic tone and could theoretically augment adverse reactions when combined with acetylcholinesterase inhibitors such as donepezil

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