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Sorafenib causes the production of P62, which inhibits NRF2 degradation and promotes the inactivation of KEAP1, followed by the activation of heme oxygenase-1 (HO-1), quinone oxidoreductase-1, and ferritin heavy chain-1, which enhances NRF2 nuclear localization

2008 May;66(5):250-5

Doses of additives and their manner of application were decided on the results of our previous in vivo experiment with rabbit-derived bacteriocin-producing strain E

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