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Tabe Y, Sekihara K, Yang H, Saito K, Ruvolo V, Taka H, Kaga N, Miida T, Andreeff M , Spagnuolo PA, Konopleva M

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Datele disponibile susin rolul su central n aprarea organismului mpotriva stresului oxidativ

The dependence of LicoAs protective effects on Nrf2 was unequivocally established through Nrf2 knockdown experiments

EZH2i increased genes related to FA mobilization from cellular stores such as ATGL, responsible for triacylglycerol (TAG) catabolism whose activity could be prevented by the concomitant upregulation of its inhibitor G0S2, potentially explaining the increased LDs content