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Glutathione or GSH, is the most powerful naturally occurring antioxidant in all human cells

showed that intracellular glutamate accumulation following cyst(e)ine depletion or system x C - inhibition is a key contributor to the induction of ferroptosis, and glutamate toxicity can be alleviated by converting excess glutamate to -glutamyl-di- or tripeptides via promiscuous enzymatic activities of glutamate-cysteine ligase catalytic subunit (GCLC) 12

tabacum cell suspension to elevated temperature (55C) also resulted in increased GR activity (Locatto et al., 2009)

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