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Plant-nanoparticles enhance anti-PD-L1 efficacy by shaping human commensal microbiota metabolites

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All experiments were carried out in triplicate, employing ascorbic acid as the reference standard under identical experimental conditions 92,93

We also observed an upregulation of Nos1 (encoding nitric oxide synthase, NOS1) and Ntrk1 (encoding neurotrophic tyrosine kinase receptor 1, TrkA) in this pathway

FIGURE 1 Unlike other growth factors and their receptors, HGF binds to the c-Met as a unique ligand (Naldini et al., 1991b