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(2001) Cellular distribution and function of soluble guanylyl cyclase in rat kidney and liver J

Worldwide, it is esti- verse effects on the growth and development mated that nearly 1 billion people are at risk of the infant.2,4 of iodine deficiency disorders (IDD).1 Iodine deficiency, both in utero and during early Although a diet low in iodine is the primary childhood, can impair mental development cause of goiter and IDD, other dietary factors and is the most prevalent cause of preventable can exacerbate the deficiency

Multiple risk loci are enriched in lysosomal function and immune-inflammatory pathways, indicating that genetic background contributes to disease onset by disrupting protein homeostasis and the immune microenvironment

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J Thorac Cardiovasc Surg 165(5):1743-1750, 2023