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JAMA Psychiatr

Roberts, J.C

Studies have shown that tamoxifen resistance is associated with IGFBP-1 accumulation and that the overexpression of IGFBP-1 promotes tamoxifen resistance in breast cancer cells by activating the ERK pathway, which can be reversed by knocking down IGFBP-1 (134)

Over the last few years, the ECS has attracted significant attention due to the connection between endocannabinoids, their lipid analogues, and various redox-dependent processes (Jorgaevi et al