Among these, amino acids are crucial in stress mitigation for fish as they serve as fundamental components in various physiological and biochemical processes that enhance their ability to cope with and recover from environmental and physiological stressors [5, 29]
Moreover, with ageing inter-cellular communications change with hormonal changes, immune-system drift and the senescence-associated secretory phenotype (SASP) affecting distant cells
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The low concentrations of ceramides measured after a TBI, in combination with increased SM concentrations, could indicate that a conversion of ceramides into SMs has taken place

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