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Therefore, the deletion of the GDH2 gene will certainly impact on the catabolism of arginine and proline, considering that Gdh2 is the main enzyme capable of converting glutamate into -ketoglutarate through the reduction of NAD +

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Cancer 51 , 13811388 (2015)

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In addition, the medical cost of reduced productivity while at work (presenteeism) or absent from work (absenteeism) due to weight-related health issues was estimated to be $15.5 billion in 2019, representing 0.9% of the gross domestic product

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