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Like the wild-type MBP-PIF4 bHLH , the mB version, which alters only the basic motif, showed both dimers and high-molecular-weight multimers, whereas the multimer band was barely visible in the mBH version, which additionally targets the first helix (Fig

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It reflects the threshold where copper peptides demonstrate follicle-stimulating activity without triggering the inflammatory cascade that copper overload produces

The blockage or reversal of sequestration will reduce or eliminate the microvascular occlusion generally associated with the pathology of this type of malaria, which, again, can lead to destruction of the PE by the host