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We demonstrated that the GSH increase in CO23RFLC conferred to this strain a clear advantage in counteracting oxidative toxic agents while assignment of other roles, such as a more efficient elimination of the drug from the cell, should be considered more speculative

G.SeifritzE.et al

For example, as a member of the mitochondrial transporter family (SLC25), SLC25A22 can promote glutamate to enter the mitochondrial matrix, thus accelerating the GSH synthesis process