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Serum bilirubin levels are normal in 60% of patients at diagnosis (Talwalkar & Lindor, 2005), but bilirubin levels will markedly rise as PSC progresses

Haake M, Mller H-H, Schade-Brittinger C

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McMillan NA, Carpick BW, Hollis B, Toone WM, Zamanian-Daryoush M, Williams BR (1995) Mutational analysis of the double-stranded RNA (dsRNA) binding domain of the dsRNA-activated protein kinase, PKR