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Below, each gene is linked to a specific piece of the MCS puzzlefor example, CYP2C9 and GSTM1 affect how you metabolize and conjugate chemicals, SOD2 and CAT influence antioxidant defenses, and TRPA1 and ADORA2A tie into sensory irritation and inflammatory signaling

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Furthermore, in the structures of TyrBm with KA at the entrance of the active site this interaction was also found to be important for KA stabilization 22

15-18 Under normal circumstances, this toxic metabolite reacts with sulfhydryl groups in glutathione, converting it to harmless metabolites before being excreted in the urine