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Fertil Steril 2008;89:1064-1068 Mansour G, Aziz N, Sharma R, et al

NGF and BDNF signaling control amyloidogenic route and Abeta production in hippocampal neurons

All values are means and 95 % CI of the mean ( P 005)

Second, given that the activation of GSR and TXNRD1 are involved in ROS elimination, if the LCS3-triggered lethality of VRK2-KO PC cells could be attributed to inhibiting the activity of both GSR and TXNRD1, then the level of ROS generated by LCS3 should have been much higher than those produced by the treatment of the TXNRD1 inhibitor auranofin