deficiency causes demyelination affecting sensory and motor nerve pathways Common presentations include peripheral neuropathy (glove-and-stocking paraesthesia), unsteadiness, cognitive impairment, and mood changes Neurological symptoms can occur before anaemia develops and may not correlate with serum B12 levels UK treatment for neurological involvement requires hydroxocobalamin 1 mg intramuscularly on alternate days initially, then every two months Treatment should not be delayed whilst awaiting test results when neurological B12 deficiency is suspected, as delays risk permanent damage At-risk groups include older adults, vegans, post-bariatric surgery patients, long-term metformin users, and those exposed to nitrous oxide Table of Contents Not sure where to start
Prostaglandin F2alpha receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined medium
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MIC-B12 is a compounded injectable dispensed under a valid prescriber order, most often by a 503A compounding pharmacy
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