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Inclusion criteria: all participants must: be 65 years of age be attending a primary healthcare centre for consultation on some medical matter provide their informed consent to be included have a serum B12 concentration of 200 pg/ml at 4 months in over 70% of patients

TNF-, tumor necrosis factor

The transition to a durable healthcare platform requires moving away from research-grade peptides

Ice crystal formation during freezing physically damages peptide structure similarly to shaking

Results showed curcumin preserves TERTrelated antiapoptotic function, potentially protecting brains intoxicated with Acrylamide [239]