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Exercise caution or seek alternatives in patients with prior anaphylaxis to parenteral vitamins

As a cofactor, cobalamins are essential for two cellular reactions: the mitochondrial methylmalonyl-CoA mutase conversion of methylmalonic acid (MMA) to succinate, which links lipid and carbohydrate metabolism, and the activation of methionine synthase, which is the rate-limiting step in the synthesis of methionine from homocysteine and 5-methyltetrahydrofolate

B12 injections are becoming a more and more popular alternative

A B12 injection is made-up of artificial B12 vitamin and is used to treat low B12 levels in the body