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Individuals with alcohol use disorder are more likely to consume excessive amounts of alcohol in short periods, often ignoring physical warning signs

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There are multiple contributing factors influencing this trend, including aggressive prescribing of opioids in the past decade, the emergence of synthetic opioids such as fentanyl, and the increasing adulteration of street drugs with other substances such as xylazine (70)(71)

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However, researchers say the death was not vaccine-related and the trial should continue