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However, as ammonia accumulates to higher concentrations, it may disrupt the initiation and degradation stages of autophagy (e.g., inhibiting autophagosome-lysosome fusion), impairing autophagic flux and promoting autophagic cell death (109, 115)

Rats were treated with increasing doses of THC as described previously [5]: 2.5 mg/kg (PND35-37), 5 mg/kg (PND38-41) and 10 mg/kg (PND42-45) or with vehicle

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Acute diseases generally develop quickly and usually only last for a few days or weeks

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