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Front Microbiol 7, 947

[137] found that the sesquiterpene CA-4 in the seed extract of Artemisia argyi exerts anti-inflammatory effects through a dual mechanism: 1) Inhibiting the MAPK pathway (phosphorylation of ERK/JNK), down-regulating the expression of iNOS/COX-2, and blocking the polarization of M1 macrophages