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Jachman-Kapuka et al., Cross-Section of Neurological Manifestations Among SARS-CoV-2 Omicron SubvariantsSingle-Center Study, Brain Sciences, doi:10.3390/brainsci14111161

Briefly, rat lung parenchyma samples were rinsed with DMEM, cut into 12 mm 3 pieces and digested for 60 min in collagenase (1 mg/ml) at 37 C in a shaking incubator

Subsequent studies have corroborated these findings and expanded upon them

However, in IBD the balance between these two populations is disrupted, with a reduction in tissue resident macrophages and an increase in infiltrating macrophages, which have a more pro-inflammatory phenotype [3,4,5]

doi: 10.1007/BF02682106