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While beneficial for normal growth, it poses a theoretical risk of accelerating the growth of existing or dormant cancers (for example, prostate, breast, colon) by inhibiting apoptosis (programmed cell death) and driving cell replication

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In a clinical study, researchers evaluated cDC1 vaccine pulsed with HER-2 peptide in early invasive breast cancer (IBC) and ductal carcinoma in situ (DCIS) ( in vitro and induced a long-lasting Th1 response in 27 patients with DCIS who overexpressed HER-2 (Sharma et al., 2012

Patients that were able to titrate up to at least 50 mg in the drug group, however, had higher improvement rates 66% (significantly greater than the placebo group)

Planning ahead prevents gaps in your protocol, and the peptide cost calculator can help you estimate total research costs across the full escalation schedule