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Gastrointestinal conditions Some gastrointestinal conditions may affect how vitamin B12 is digested or absorbed, such as: history of gastrointestinal surgery celiac disease Crohns disease pernicious anemia infections, such as from Helicobacter pylori bacteria or parasites pancreatic insufficiency or cancer bowel cancer folic acid deficiency small intestinal bacterial overgrowth Vitamin B12 injections may be more helpful for people with gastrointestinal conditions than oral products

Attributing the result to the shot is a reasoning error, not a finding

Some feel a change the same day

It can be stored at room temperature in a cool, dry place away from light, though reconstituted solutions still benefit from refrigeration

Still later I should have taken more pictures to show that it took many months for the fever blister marks to fade