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Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

circa 95% of infections occur in sub-Saharan Africa

10.3389/fonc.2021.597536 51 QiaoP.NingL.ChenJ.TangY.ZhaoR.ChenG.et al (2024)

Despite these advances, however, it remains a manageable but incurable disease

Follow-up study to the landmark observation that disruption of the PGPs failed to evoke a disease phenotype, but did render mice extraordinarily sensitive to ivermectin