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For example, SREBP-1c can activate the transcription of MAT2A (encoding MAT 1 subunit), a key enzyme in SAM synthesis, in response to cellular lipid levels

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"I think it was a tainted supplement," Ogunjobi said

The study was carried out using the dynamic stimulator of the human intestinal microbial ecosystem (SHIME ) and mouse hippocampal cells (line HT-22) as a model of neuronal cells in vitro