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Imai H, Hirao F, Sakamoto T, Sekine K, Mizukura Y, Saito M et al

705 Albiflorin not only inhibits neuronal ferroptosis by reducing the levels of lipid peroxide and iron and regulating ferroptosis-related proteins, but also inhibits microglia activation and reduces the production of pro-inflammatory cytokines, thereby promoting motor function recovery after SCI in rats

It also suppresses pro-inflammatory cytokines, reducing inflammation by regulating multiple cellular pathways, which is a major contributor to age-related decline or diseases

As the only extracellular enzyme in the GPx family, GPx3 is an essential enzyme that is responsible for removing ROS products during normal metabolism or oxidative damage in healthy tissues [76]

These functional improvements suggest that senescent cell clearance doesn't just change biomarkers it translates to measurable physical performance gains in aged animals