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All in all, despite recent progress in the field, the detailed mechanisms of ferroptosis are still largely unknown and a significant amount of research remains to be developed in this new exciting area of research

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However, it can sometimes progress to acute liver failure (ALF), leading to serious complications or the need for a liver transplant

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The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation