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Research on epithalamin and epithalon dates back to the 1980s, overseen mostly by Vladimir Khavinson, an accomplished scientist who is well-known for his pioneering work on other peptide bioregulators including Vilon

measured MMP1, MMP2, TIMP1, and TIMP2 gene expression in human adult dermal fibroblasts exposed to GHK-Cu at 0.01, 1, and 100 nanomolar concentrations and found dose-dependent increases in both MMPs and their inhibitors 11

Applying a medical-grade GHK-Cu serum immediately after treatment can improve recovery time, minimize redness, and boost skin regeneration

Epithalon also seemed to inhibit the activity of Caspase-3, a crucial enzyme believed to facilitate apoptosis (programmed cell death)

10.1089/ars.2006.8.1865 Antioxid Redox Signal