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First paper indicating that regulating malony-CoA in the hypothalamus is important for regulating energy intake

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and the decision to submit the article for publication

doi: 10.1210/jc.2010-1587 77 Johns Hopkins University

Notably, increased NAD+ levels also activate NAD+dependent signaling pathways such as sirtuins (SIRT1/SIRT3), further enhancing mitochondrial biogenesis and energy metabolism