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PCa ranks as the second most prevalent malignancy and the sixth foremost cause of cancer-related mortality among men worldwide, with approximately 1.46 million new cases and 396,000 fatalities documented in 2022

they are the physical manifestations of a cellular engine that is misfiring

doi:10.4049/jimmunol.181.3.2103 2019 The Author(s)

A growing body of evidence demonstrates that lactylation is widely involved in regulating key malignant phenotypes of HCC, including proliferation, metastasis, stemness maintenance, chemoresistance, and immunosuppression

3.2 The heterozygous mutation of EpCAM increased the expression of matrix metalloproteinases and the activation of MAPKs in the colon of DSS-induced mice To further evaluate the severity of the inflammation at molecular levels, the expression of the colonic abundant matrix metalloproteinases (MMPs) was subsequently checked