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Another mechanism of ER stress associated with -syn is the inhibition of protein trafficking to the Golgi apparatus, which interferes with protein maturation and induces stress [119, 120]

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Collectively, these studies underscore the pivotal role of -syn in PD-related ferroptosis and neurodegeneration, providing a rationale for therapeutic strategies targeting ferroptosis

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Research Applications Key Differences BPC-157 is more associated with cell signalling and repair pathways TB-500 is more associated with cell movement and structural reorganisation Practical Considerations for Comparative Research For researchers designing comparative or combination protocols with BPC-157 and TB-500, four practical points come up repeatedly: Reconstitution both compounds are supplied lyophilised and dissolve readily in bacteriostatic water