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The FEBS J 283(3):413424

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Its unique, multi-faceted mechanism of action makes it a subject of intense interest in metabolic research

(Phila) 2013, 6 (8), 801810

Clinically, elevated IS levels correlate strongly with increased cardiovascular event incidence in patients with CKD, primarily mediated by inducing oxidative stress in endothelial cells (Lin et al., 2012