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Jungas T, Motta I, Duffieux F, Fanen P, Stoven V, Ojcius DM

sloughing germinal epithelia of seminiferous tubules into the lumen with the absence of spermatogenic stages, exfoliation of germ cells with an absence of spermatozoa and presence of cellular debris, immature germ cells (black square), and vacuolation between germ cells (black arrow)

We also compared baseline values with those from combination therapies involving the intravenous administration of DMPS plus CaEDTA (calcium ethylenediamine tetra-acetic acid), and DMPS plus ZnDTPA

10.1002/dev.21604 [DOI] [PubMed] [Google Scholar] 177

Taken together, the versatile capabilities of mitochondria in bioenergetics and biosynthesis could trigger lipid peroxidation to ferroptosis