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doi:10.1111/iwj.14748 146

Notably, mutations and defects in SOD1 have been associated with oxidative stress, neuroinflammation and mitochondrial dysfunction

Haematologica (2007) 92(9):116572

When the calcium binds to a protein called synaptotagmin, on the vesicles' surfaces, synaptotagmin teams up with other proteins to tug some of the vesicles, winch-style, closer and closer to the neuron's surface membrane until their enclosing membranes fuse with it, spilling the vesicles' contents into the surrounding environment