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We excluded those with poor response to levodopa to differentiate from vascular parkinsonism, Parkinsonplus syndrome, or where PD is likely secondary to stroke, druginduced, postinfectious, inflammatory, or traumatic etiology

During biochemical processes that normally take place in living cells, many types of free radicals are generated: oxygen-, sulfur-, bromide- and chloride- centered species [Halliwell & Gutteridge, 2007]

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An increase in activated microglia has been observed in both PD patients and healthy older people, indicating that various triggers might induce a proinflammatory shift with age (57)

doi: 10.1053/j.gastro.2007.01.033 29