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Additionally, NLRP3 inflammasome was identified as a pivotal element in the inflammatory cascade of UC, which is a multi-protein complex that activates caspase-1 to convert pro-inflammatory cytokines into their active forms, thereby leading to the perpetuation of mucosal inflammation [7, 8]

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However, a significant proportion of patients are still refractory to pharmacological treatments, so the development of new drugs targeting the underlying mechanisms of UC is necessary to achieve optimal disease control

PRP for Heel Pain Plantar fasciitis can become an overwhelming, persistent condition that severely limits daily life