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Appearance: Fluid-filled blisters that may ooze and crust over

Oral formulations are mainly discussed for gastrointestinal applications, but research remains limited

The low pH of exfoliating acids and other acidic ingredients can weaken the peptide-copper bond, potentially limiting effectiveness and increasing the risk of skin irritation and oxidation

Physicians, when prescribing ketorolac tromethamine, should inform their patients or their guardians of the potential risks of ketorolac tromethamine treatment (see Boxed WARNING, WARNINGS, PRECAUTIONS, and ADVERSE REACTIONS sections), instruct patients to seek medical advice if they develop treatment-related adverse events, and advise patients not to give oral ketorolac tromethamine to other family members and to discard any unused drug

2014 Jan-Feb;40(1):3-11.