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Longer-acting (in humans) beta-2 adrenergic drugs tend to be more lipophilic and thus remain in the presence of a receptor for a longer time

By integrating excitation light sources at specific wavelengths with fluorescence detection modules and employing membrane potential-sensitive fluorescent dyes, this platform holds the potential to not only continuously monitor bacterial growth curves but also to capture rapid biochemical events, such as membrane depolarization, occurring under antibiotic pressure in real time and synchronously

Among the naphthoquinones, LS826 [37] behaved as a selective TGR inhibitor, with an IC 50 of 8 M, but as a poor inhibitor of the human enzymes

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Toxicol Mech Methods 23(6):396401