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The cystine-glutamate antiporter system (system Xc ) imports cystine, which is converted into cysteine, the rate-limiting precursor for GSH biosynthesis

J Hepatol 2006;44:784-790

On the benefit of probiotics in the management of pouchitis in patients that underwent ileal pouch anal anastomosis: a meta-analysis of controlled clinical trials

The EGL-9 protein uses molecular oxygen to hydroxylate the hypoxia-inducing factor, or HIF, inhibiting HIF transcriptional activity

It is possible if not likely that pressure affects these manifold processes via mechanotransducer mechanisms (such as mechanosensitive TRPV4 and TREK-1 channels and integrins