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The NICE Clinical Knowledge Summary on B12 and folate deficiency recommends assessing the underlying cause before choosing a treatment path, which is why speaking to a pharmacist or GP first matters

The injection can be a standalone treatment, but its more commonly incorporated into other treatments, such as physical therapy

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Gastrointestinal adverse events, primarily nausea, vomiting, diarrhea, and constipation, are the predominant side effects, occurring most frequently during dose escalation and generally diminishing with continued treatment